"Giving a single government agency the power to arbitrarily set the price of medicines with little accountability, oversight or input from patients and their doctors will have significant negative consequences long after this administration is gone," Pharmaceutical Research and Manufacturers of America (PhRMA) President Stephen J. Ubl said in a statement.
Oh.. I can see it now. Patients and their doctors begging for more expensive drugs.. The government saying, "Yeah! These fucking people aren't paying enough! Let's negotiate with the drug companies for HIGHER prices! That will get us reelected!"
Get fucked, Stephen J. Ubl, president of Pharmaceutical Research and Manufacturers of America.
There's no one answer here. It's going to take a lot of trial and error and experimenting. All of the issues you mention are going to have to be addressed individually as well. There is never going to be a single tool to do this for you.
As far as tracking state over time, standing up a proper, modern monitoring stack will help tremendously. If you send logs to loki, collect metrics with Prometheus or OpenTelemetry, and graph them both with grafana, you should have really great insights to whatever is happening.. It's never going to be finished though. It's always a work in progress.