Something I've seen far less reaction to than I expected? While the Switch 2 looks like it takes standard MicroSD cards, it DOESN'T. It takes the fairly obscure MicroSD Express standard! I can't even BUY an SD Express card locally right now! It seems likely, at launch, that Nintendo's branded cards will be the only ones people can get that will work with it!
The Switch 2 has 256GB of onboard storage, much more than the Switch, it is true. But it's also backwards compatible with the Switch, and lets users bring their old digital library over with them. I have a 256GB card in my Switch, it's nearly full, and it doesn't have my whole library on it! If I got a Switch 2, I'd have it filled up on day 1!
And the MicroSD card issue won't be obvious to most buyers. Parents will get their kids Switch 2s, and wonder why their old card won't work with it. It'll look to them like the Switch 2 or the card is broken, unless they implement a physical lock against incompatible cards, and I don't know if SD cards even support those. Also, SD Express cards are more expensive than standard ones.
This could end up being a debacle almost on the scale of the price (which, as others have noted, isn't even Nintendo's fault entirely).