this post was submitted on 15 Dec 2024
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[–] [email protected] 31 points 6 days ago (4 children)

Because chronic diseases are difficult to cure? A solid portion, like diabetes, or cancer, are a whole host of different causes in a costume.

Anything that can be easily cured/trivially managed, or outright prevented isn't considered a chronic disease any more. Beri-beri and Scurvy are non-issues today. Diabetes and AIDS aren't the death sentences they used to be.

Medical research being deliberately gatekept because a cure would be unprofitable is conspiratorial thinking, and isn't really reflective of reality.

A single dose cure for a chronic illness would be huge, and a lot of places would throw money at one if it existed, even if the cost was several orders of magnitude higher. No insurance, public health scheme, nor medical clinic would want a patient to take a constant course of medication, when they could have one, and be done. It'd be better for them, and patient quality of life. Even for the medication companies, they get to be in history books, and can get instant income, where a long term scheme might have patients dropping off for one reason or another.

[–] [email protected] 10 points 6 days ago

And if someone cures it first that's it, they win the whole pot until generics are approved.

[–] [email protected] 5 points 6 days ago

lots of chronic diseases we have today are either degenerative or genetic, so it requires new fancy tools like gene therapy to rework lots of cellular biology at very low level. small molecule drugs can manage these to some degree, but these were a thing for like 50, 70 years now so that's why these are a thing

[–] [email protected] 5 points 6 days ago

Thank you. You expressed everything I wanted to say.

Gatekeeping cures to illness just isn't true.

[–] [email protected] 3 points 6 days ago

I guess the sad thing is, that given the way things are, i cant blame people for thinking this way. Because be honest. Would you put it past them to not do it?

I can 100% see healthcare and pharmaceutical companies doing this for profits.

[–] [email protected] 30 points 6 days ago (1 children)

If a disease is curable, it isn't chronic, now is it? This is a dumb take.

[–] [email protected] 8 points 6 days ago* (last edited 5 days ago) (2 children)

Yeah, this is a common truism that angry people confuse with actual criticism.

It would, in fact, be extremely profitable to develop a cure for something chronic. If you could make and sell one pill that cures AIDS, for instance, then you would become very rich (not to mention famous).

That's not a defense of capitalism. For-profit healthcare is a dystopian nightmare. When you consider that the AIDS cure would be too expensive for most people to buy, and only poor people would suffer from the disease, you should remember that that's how it is now! Poor people cannot afford cures available to rich people, cures for preventable diseases, cures for treatable and manageable diseases, cures for addiction and obesity. Poor people cannot afford to stop working long enough to seek treatment for basic aliments.

So no, scientists and doctors aren't conspiring to avoid working on cures in favor of treatment for chronic conditions. They're just going where the money is. They absolutely would cure any disease if it were possible, they just wouldn't share it with the world.

[–] [email protected] 3 points 6 days ago

For the record PrEP exists and it is pretty effective in preventing getting HIV (the virus that causes AIDS). Yet another reason the OP is dumb. Also, HIV can be prevented from turning into AIDS now, too.

[–] [email protected] 0 points 6 days ago

If you could make and sell one pill that cures depression, you would get killed by the people making antidepressant that you have to take daily.

But count on a worldist to suck the corpodick

[–] [email protected] 26 points 6 days ago (3 children)

Of the 10k or so identified chronic diseases, about 95% of them are genetic

Given that we, as humanity, have just barely started ( in research time. From 1987 to 2024, that's almost 40 years of research, and development, basically nothing on one of, if not the toughest field in the world, and we are still doing breakthroughs on it)

In fact this research has been the cause of improving the quality of life for people with these diseases as care for the patients during test reveals more data.

Also remember, low understanding of the technology, particularly AI which is extremely helpful in these types of researches and past eugenics fears have marred the general zeitgeist for years, which may also cause early adoption to be difficult.

I mean come on, people are still scared about genetically modified food.

And also, another one thing to remember is that a lot, like 80% of these diseases, have an inherent risk for the life of the patient, which slows the research as this limits the amount of data you can get.

So, we are not yet at the point of cracking the genetic makeup of a disease, chugging it into a bioreactor, and whipping billions of potential enhanced cures adapted for the specific body chemical makeup, but we are getting there.

So yeah there is no conspiracy.

Billions of dollars have been spent only on cancer research, imagine for the rest of diseases. If a government had cancer cure done for X type of cancer, they'd deploy that shit like Doritos locos at the mall and ensure themselves indefinite reelections forever.

It's just really, really, RIDICULOUSLY difficult.

But, we are humans, difficult for us, is an old friend

[–] [email protected] 3 points 6 days ago

I've grown up fascinated with several diseases and was eager to study them and find treatments that would better and prolong the life of the patients. By the time I was done with university my disease pet peeves were already very well managed. Take cystic fibrosis, a disease that was still considered a childhood disease when I was born in the 90s. With trikafta and other treatments CF patients now climb mount everest and whatnot. They have kids, back in school I learned that the few cases who made it to adulthood were infertile because of their viscous mucus. Like, I would love to work on an mRNA based gene therapy for it, but it seems almost unnecessary, given how manageable the disease has become.

I also agree and want to stress what you are saying about the acceptance of gene therapy/ GMOs in general. I am in Germany and people here are insanely against GMOs of any kind. Manipulating the human genome is so far off the rails for the vast majority, I mean there is still so much hate against GMOs in food, we are nowhere near trying to use gene therapy on a broad scale. Let alone that to actually cure a genetic disease, you would have to undergo the gene therapy while you're still a zygote. This is simply illegal here. Our research opportunities are severely limited on genetic manipulation.

[–] [email protected] 4 points 6 days ago

This.

Yes, yes, there are conspiracies here and there, but these days we can't have any reason anymore, everything must have an evil genius behind it.

This is just another case of "it's not that easy"

[–] [email protected] 10 points 6 days ago* (last edited 6 days ago)

That is not how modern capitalism works. Modern capitalism works in 5 years. CEO have figured out that they don't need to work for the shareholders but make it seem like they do. CEO wants to get their bonus and they get their bonus if the shareholders are happy and usually the shareholders have short term interests too. So for a CEO, it is more profitable to take actions that generate more profit in short terms.

Which is why there are mass hiring and firings. Those things are a huge waste of resources but it look good on you if you can sell it right to the shareholders. You are willing and able to react quickly.

So a cure for cancer would be sold as soon as possible because whoever has the patent, would make billions (short term). Remember biotech and their COVID vaccine?

The problem becomes finding a cure and a CEO doesn't have any interest to heavily invest in finding a cure if the cure is not "around" the corner anyway, as that wouldn't be very short term minded of them. But as this problem exists for any illness, the ones most likely to be treatable through publicly funded Research will get the funding to make the medicine and put a patent on it.

Edit: they don't kill you for profit. They don't heal you for profit. For their profit, they act. You just happen to be acted on.

[–] [email protected] 14 points 6 days ago

This is wrong.

It's applying a good observation incorrectly.

There's enough awful greedy shit to keep us busy. No inventing more of it.

[–] [email protected] 13 points 6 days ago

OP in 1939* "Why isn't there a cure for the consumption?! must be because the travelling physicians wouldn't make any money!"

This is a moronic take.

[–] [email protected] 5 points 6 days ago (1 children)

Idiotic conspiracy theories are idiotic

[–] [email protected] 1 points 5 days ago

Idiotic coincidence theories are idiotic

[–] [email protected] 1 points 6 days ago

Did you confuse capitalism with morality again?

This has got to stop happening

[–] [email protected] 1 points 6 days ago (1 children)

Ah yes that's why incredibly breakthroughs in medical science have completely stopped happening!

[–] [email protected] 1 points 6 days ago (1 children)

Can you post something that's being actually available? A day old video that claims diabetes is now curable doesn't really mean much

[–] [email protected] 2 points 6 days ago (1 children)

Bro do you have any idea how difficult is to cure diabetes

[–] [email protected] 7 points 6 days ago

I do. That's why somebody pointing a video on YouTube as proof for anything is bonkers for me.

[–] [email protected] 177 points 1 week ago (3 children)

Or, chronic diseases which have been effectively cured aren't considered chronic diseases anymore?

[–] [email protected] 45 points 1 week ago

Stop with your logic on the Internet!

And yes, the vast majority of the apparatus that is capitalism is evil, before anyone wants to think I'm simping for it.

Hell, most chronic disease cures are done by the evil and completely untrustworthy propaganda machine that is the government.

[–] [email protected] 25 points 1 week ago (5 children)

Yeah, we've cured a ton of previously chronic diseases. I don't know what planet these people live on. We've even effectively cured certain cancers in our lifetimes, and more will come. It's also just much harder to cure something than treat something.

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[–] [email protected] 76 points 1 week ago (1 children)

Capitalism or not the claim would be true, chronic diseases are defined by their lack of effective cure.

[–] [email protected] 31 points 1 week ago (6 children)

Completely true. But there would be fewer of them.

It’s crazy that when my research team comes up with a therapeutic target we believe might lead to curing a disease, we get crickets from drug companies. But when we present therapeutic targets for long term treatment, we get lots of interest.

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[–] [email protected] 40 points 1 week ago (7 children)

Tiring ass conspiracy theorists.

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[–] [email protected] 33 points 1 week ago (2 children)

Just saying, "it's capitalism's fault," is not entirely incorrect, but it is definitely oversimplifying. Chronic diseases are complex, incredibly challenging to solve, and can vary a great degree by individual.

The government gave the NIH a billion dollars to study long COVID and the result ... fuck-all. Literally all they did was loosely define some things that the enormous and growing patient community already knew. No treatments, no diagnostics, nothing.

To be clear, capitalism certainly plays a substantially antagonistic role in solving chronic illness, but just throwing money at a problem doesn't solve it either.

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[–] [email protected] 31 points 1 week ago

This is such a lie. This only works if you assume no other people will ever develop one of those illnesses. Even if all acquired illnesses are ever eradicated, big pharma companies will still make bank off hygiene products, makeup, and Aspirin. Pharma companies don't just sell treatments and cures. Duh.

[–] [email protected] 26 points 1 week ago

Making cure when everyone else makes a treatment means that you can undercut everyone and eat their lunch so incentives are there

part of the problem is that developing treatments is easier and can rely on more conservative, safer assumptions while cures require more early stage risky research

besides chronic diseases that do have cures aren't considered chronic anymore. the rest are problems with insurance that doesn't want to cover single expensive cure over cheaper but recurrent treatment that might add up to more

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