Science

12955 readers

30 users here now

Studies, research findings, and interesting tidbits from the ever-expanding scientific world.

Subcommunities on Beehaw:

Space

Be sure to also check out these other Fediverse science communities:

This community's icon was made by Aaron Schneider, under the CC-BY-NC-SA 4.0 license.

founded 2 years ago

MODERATORS

[email protected]

I always suspected my antidepressants were messing with my ability to party. (pure.johnshopkins.edu)

submitted 2 months ago by [email protected] to c/[email protected]

6 comments fedilink hide all child comments

you are viewing a single comment's thread
view the rest of the comments

[–] [email protected] 8 points 2 months ago* (last edited 2 months ago) (1 children)

this has been known among users of these drugs for quite a while now. They bond to the same receptors, so they interfere with each other. You can mitigate this a bit by going 24 hours without your SSRI/SNRI (ie skipping the dose that would precede the trip), and increasing dose of the psilocybin by ~1.5x. Or so I hear

[–] [email protected] 6 points 2 months ago (1 children)

Also pretty dangerous to do MDMA without pausing your SSRIs and just about deadly to do them when on MAOIs

[–] [email protected] 2 points 2 months ago (1 children)

true, but MDMA is a different drug

[–] [email protected] 2 points 2 months ago

Yeah, but its a serotonin agonist, so it has a compounding effect