this post was submitted on 25 Nov 2023
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The lab-born primate, developed by Chinese scientists, made history as the world's first live-born "chimeric" monkey. And: he glowed! Green!

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[–] [email protected] 46 points 11 months ago (1 children)
[–] [email protected] 5 points 11 months ago (2 children)

Ya I do have trouble with experimentation like this.

Sure, you made his skin glow green, but maybe it burns like fire 24/7 and you'll never know since it can't tell you.

[–] [email protected] 24 points 11 months ago

If it burns it probably creates a sensation called pain.
As it's a baby it very likely would be very vocal about pain.

[–] [email protected] 10 points 11 months ago

We'd be able to know by studying the monkey. Not even for a long time either.

[–] [email protected] 22 points 11 months ago (2 children)

ITT: people not reading a single line of the article

[–] [email protected] 8 points 11 months ago (1 children)
[–] [email protected] 3 points 11 months ago

Everywhere. This is not unique to any social media platform.

[–] [email protected] 14 points 11 months ago (3 children)

It’s great that peak scientific minds are trying to create green, glowing monkeys. It’s not like humanity is bothered by plethora of problems. Let’s chill and torture some monkeys instead.

[–] [email protected] 28 points 11 months ago (1 children)

Yeah they just doing this for no reason /s.

Did you even read the article?

[–] [email protected] -1 points 11 months ago* (last edited 11 months ago)

Did you? It says that it at one point MIGHT be useful to chimerize the monkeys to research neurodegenrative diseases. Making it glowing was just to make shit easier for them, not for any scientific purposes.

And yeah, I get it, scientific breakthrough comes with a cost, but there’s reason why primates are not generally getting chimerized…

[–] [email protected] 25 points 11 months ago (2 children)

You probably fail to understand that the end goal is not to make green glowing monkeys for shits and giggles.

[–] [email protected] 4 points 11 months ago

He's going to break the Sarcasm-O-Meter, please be careful. It never stood a chance at life :/

[–] [email protected] 1 points 11 months ago* (last edited 11 months ago)

No shit. I thought they wanted to have a mobile lantern.

[–] [email protected] 13 points 11 months ago (1 children)

Ya but how many asses does it have?

[–] [email protected] 1 points 11 months ago (1 children)
[–] [email protected] 1 points 11 months ago

When will we learn not to play God half-assed

[–] [email protected] 9 points 11 months ago (1 children)
[–] [email protected] 17 points 11 months ago (1 children)

I link to articles I’ve actually read. I didn’t read that one because I read this one, so I didn’t link to it. That’s why.

[–] [email protected] 4 points 11 months ago (1 children)

Fair enough. The original is a bit more informative than the re-write, I think.

[–] [email protected] 3 points 11 months ago

I would love a cultural norm of always posting the actual study alongside write-ups

[–] [email protected] 8 points 11 months ago (2 children)

Why was the monkey euthanized, though?

Besides killing it being a waste of life, wouldn't keeping the monkey alive be a good way to study the long term effects of this experiment?

[–] [email protected] 14 points 11 months ago

the article states that the primate was not healthy when it was born, so it needed to be euthanized.

[–] [email protected] 6 points 11 months ago* (last edited 11 months ago) (1 children)

They can't live for very long. It's why I kinda think this work is somewhat unethical - even if it brings about breakthroughs that could help millions.

[–] [email protected] 6 points 11 months ago* (last edited 11 months ago) (1 children)

This tends to be an unpopular opinion, but I completely agree. I believe it's unethical to do experiments like this on animals that cannot consent, but have a clear capacity for suffering, including on a conscious level.

Even lab rats show a capacity for empathy [1], and they will stop pulling a lever to feed themselves if they see the rat in the subsequent cage is electrocuted. [2]

Monkeys (and other animals) can understand the concept inequality. [3] Inequality is a moral concept, indicating that the animal has a capacity for complex social relationships and understanding.

Monkeys were taught the concept of currency (in the form of silver discs) and soon after, they unexpectedly developed prostitution on their own. [4]

Monkeys like this are the primates of lower intelligence, mind you. I'm not even saying I condone these studies even, as I'm not convinced the ends justify the cruel means with which the experiments were conducted.

I think we should be more respectful of life, rather than subjecting it to such mass exploitation and suffering. I can admit I will value my loved ones over other animals and humans on a selfish level, but when I separate emotion from my reasoning, I don't believe it is justified for humans to exploit animals as we do for our own gains.

It's important to note the extremely unnecessary suffering of frivolous experiments on a widespread scale. One example is the LD 50 (or median lethal dose), in which animals are essentially force-fed a product (cosmetics, cleaners, medicines, etc.) until half of the test subjects die, to determine the lethal dose. [5]

Much of the time, their death isn't because of the substance itself; it's due to the quantity force-fed (stomach/organs rupturing, whatnot). This test is used on clearly nonessential products like cosmetics, and the results are often unreliable. [5]

I am not interested in debating this subject. I just wanted to share my thoughts. Things to watch out for in objection to animal rights arguments are common fallacies like the appeal to nature, appeal to tradition, and just blatant speciesism.

[–] [email protected] 2 points 11 months ago

Here is an alternative Piped link(s):

[3]

Piped is a privacy-respecting open-source alternative frontend to YouTube.

I'm open-source; check me out at GitHub.

[–] [email protected] 8 points 11 months ago

This is like how in Boku no Hero Academia where the first quirk was a baby that was born emitting light

Boku no Hero Macaque

[–] [email protected] 7 points 11 months ago

Wonder who that Gene Hackman is?

[–] [email protected] 7 points 11 months ago

The published study in question. I don’t mind an article write up, but this is a write up of a write up of a write up.

https://www.cell.com/cell/fulltext/S0092-8674(23)01087-5

[–] [email protected] 4 points 11 months ago

This is the best summary I could come up with:


A chimera, as the report explains, is an animal with more than two sets of DNA; in this case, the long-tailed macaque was created by combining two genetically distinct embryos of the same species.

As the Independent notes, scientists often use chimeric mice and rats in lab settings as a means of studying embryonic development, as well as examining disease progression in living organs and tissues.

"Mice don't reproduce many aspects of human disease for their physiology being too different from ours," senior study author Zhen Liu, a researcher at the Chinese Academy of Sciences, told CNN.

As ScienceAlert notes, in past attempts to create chimeric primates, the donor DNA was deeply underrepresented in the offspring's body tissues.

As study coauthor Miguel Esteban, principal investigator at the Guangzhou Institute of Biomedicine and Health at the Chinese Academy of Sciences, told CNN, this finding suggests that chimeric macaques could one day be useful for "modeling neurodegenerative diseases."

When the scientists combined the embryos, they added a green fluorescent protein to the donor cells — that way, they could more easily track where some of that DNA was disseminating.


The original article contains 577 words, the summary contains 186 words. Saved 68%. I'm a bot and I'm open source!

[–] [email protected] 4 points 11 months ago* (last edited 11 months ago) (1 children)

"Mice don't reproduce many aspects of human disease for their physiology being too different from ours," senior study author Zhen Liu, a researcher at the Chinese Academy of Sciences, told CNN.

But we test all our new stuff on them and write articles about Cancer cures without adding "in mice" to the title, and that gives people hope.

Edit: I understand the importance of this research but the gleeful tone feels like it was cynically added by the author (or, I don't know, an llm told to "humorify by 12%") to differentiate from the original source and just feels gross.

[–] [email protected] 9 points 11 months ago (1 children)

New medicines are usually tested first in human tissue, then on mice, and finally on humans. To oversimplify a bit, the first checks if it will do the job, while the second checks if it could have side-effects in other organs. As to why monkeys are not used instead of mice, (1) they take longer to grow up, (2) they are more expensive to maintain, and (3) experimenting on monkeys is considered more of a bad thing than experimenting on mice.

[–] [email protected] 3 points 11 months ago

I was kind of joking, kind of not, but thank you for this info.

[–] [email protected] 4 points 11 months ago

Unethical as fuck and entirely purposeless.

As usual.

[–] [email protected] 3 points 11 months ago

Fuck these guys

[–] [email protected] 2 points 11 months ago

Gene Hack-Monk as Lex Lemur

[–] [email protected] 1 points 11 months ago

That really reminded me of that southpark episode, where the scientist guy was creating monkeys with many asses :D

[–] [email protected] 0 points 11 months ago* (last edited 11 months ago)

Gene hack me to have fur and a tail, please. Hold the green glow.