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Nauseous? You won't be for long if you take ondansetron.
My wife has been on 8mg twice daily (oral dissolving and tabular at different times) + domperidone and it’s still not altered a chronic nausea that started at pregnancy. Little ones second birthday in a week, not a day without throwing up within minutes of eating or drinking anything at all - paramedics called it a starvation diet.
Not that there’s anything you can do, just getting increasingly desperate and throwing this out there in case anyone has anything to relate to this.
Super glad it’s working for you though - it’s a wonder drug for so many people!
I am so sorry that she's dealing with this. I've heard of successful treatment of intractable nausea using biofeedback therapy. The idea being that the body gets stuck in a negative feedback loop and trying to reverse that back to previous functioning.
https://www.researchgate.net/publication/314851129_Biofeedback_and_visualization_to_control_nausea_and_vomiting
https://pubmed.ncbi.nlm.nih.gov/21154016/#:~:text=Treatment%20outcome%20suggests%20that%20vomiting,bodily%20control%20and%20self%2Defficacy.
I hope this gets better for her.
Thank you!! I’ve been convinced it’s a negative feedback loop myself but I’ve not been able to find anything worthwhile on this. This is super and I’ll be taking a close look tonight to add this to my Zotero library. I’ve been shut down by doctors before on cyclic vomiting syndrome but this looks very promising and worth a shot for sure especially with that shared etiology.
Take care!
Yeah, medically cyclic vomiting syndrome is usually more associated with cannabis abuse disorder, so you're probably not going to get far trying to get that diagnosis specifically. But that doesn't mean these same treatment regimens won't help. Think of it as physical therapy for the gut and nervous system.