this post was submitted on 07 Oct 2023
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The study, published in JAMA, found these adverse gastrointestinal effects happen in non-diabetic patients using the drugs specifically for weight loss.

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[–] [email protected] 3 points 1 year ago (1 children)

Words can barely describe how awful gastroparesis is. I'd much rather be fat and diabetic than go through that again.

[–] [email protected] 1 points 1 year ago* (last edited 1 year ago) (1 children)

The study is very clearly talking about non-diabetic patients, too..

These are almost certainly people who want the weight loss primarily for aesthetic reasons rather than health ones, and may face these terrible health complications as a result. Makes it even worse, I think.

You're almost certainly better off somewhat "fat" than skinny by way of a drug like this. Especially given that "fat" is an entirely subjective measure and the "objective" measures like BMI overweight/obese are not based on points of any kind of phase change in health outcomes but are just somewhat arbitrary statistical variations. Dramatic interventions like these should be reserved for people that have dramatic need, at least until we have such an intervention safe enough and with few enough side-effects for over-the-counter sale.

[–] [email protected] 2 points 1 year ago

Yes, I understood that. Sorry I wasn't clear. I have experienced gastroparesis a couple of times, and I'm saying that it is worse than a chronic illness in my experience (I also have a couple of chronic illnesses). It's extremely unpleasant. Sure can lose weight since you can't eat anything, though.