Recently did another Plants vs. Zombies run, so I'm gonna throw this one into the mix here.
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Age of Empires, XCOM, Cities: Skylines, Divinity Original Sin 2, Starcraft, +1 for OSRS.
Without numbered groups and force attack/move tho?
kentucky route zero
If you want an alternative to Slay the Spire i can recommend Monster Train; you mainly summon different Hellspawn and cast spells, which gives it more of an Magic the Gathering feel.
If you want an ARPG fix and have thumb buttons on your mouse you can try Chronicon, don't let the gfx stop you, it's an excellent hack&slash game, and you can put all your skills onto 1 button if you like - i use the middle and the right button for most builds and thumb keys for pots
If you want a new spin on Darkest Dungeon, give Iratus - Lord of the Dead a try. Or if you played a lot of Darkest Dungeon and want more of it, try Black Reliquary, a huge (and free!) mod with a lot of new mechanics!
Going into the same direction as Into the Breach is Shotgun King - the final Checkmate. It's really fun and the higher difficulties really make your brains work out. Workshop support with lots of extra content included! Also great for Turn-based Tactics is Invisible Inc., putting you in control of an spy agency which has been hit hard and tries to recover.
For arcade games i can recommend Utopia must fall - it really captures the spirit of old arcade games, but feels real fresh. You can also go for Nova Drift, which is also an excellent arcade game.
Then there is Cultist Simulator and its spiritual successor, Book of Hours. It's basically a card based riddle game, and very atmospheric.
There is always Shattered Pixel Dungeon - it is also available on Steam or Gog, but you can download and play it for free from the link i provided.
I think your collarbone might have healed until you've finished that list, have fun!
Peggle Deluxe and Peggle Nights are awesome mouse-only (except typing name i think) casual games!
Uow about some visual novel style games like 999, Hotel Dusk (DS emulator), Ghost Trick, Professor Layton (DS emulator or mobile)
I'd say most RTS games I can think of can be played with just a mouse
Older diablo-like ARPGs didn't really rely on the keyboard too much IIRC, the modern ones do tend to rely on the keyboard a bit more
If you don't mind older games, basically the whole genre of point and click adventures is this by definition
Warcraft? Sid Meier's civilization?
Or in general any top down RPG game, like RuneScape.
Buy a mouse with a joystick or D-Pad on it. Or one of those 15 button mice meant for MMOs. Then you can play anything.
Get a giant D-pad for one of your feet to use for wasd
airborn empire is a fun city builder/resource management game
Shogun showdown
Settlers.
Lonestar if you like or are interested in roguelike deck builders. There are a lot of great games coming out in that genre, here are some others I like:
Balatro
Slay the spire
Bounty of One (not a deck builder, just a roguelike)
Edit: I just realized some of these were already suggested but I'll leave it
I installed PPSSPP on my phone and paired a switch joycon. Played through a few really good games that way when my kid required being held to sleep. I'd imagine you could pair one to your computer and find some games that you'd like.
Scarlet Hollow
If you rebind the pause/unpause button, Starsector can be played mouse only too.
Citizen Sleeper and Citizen Sleeper 2 can both be played entirely with just a mouse. No keyboard inputs needed.