MMOs are probably a good indication.
I think researchers (or just casual investigators) studied MMOs to see how people might react in a plague situation (I want to say WoW, but it might've been EverQuest).
They ended up discarding/writing off their findings because they figures that there wouldn't ACTUALLY be trolls who'd go around spreading the virus on purpose, and also that because the virus only had negative effects, no one would be doing actions that would nearly guarantee infection.
Of course, 2020 showed us that we really should've been looking at what people do in MMOs...