TLDR: So this is saying there are some genetic variants that cause cascading protein malformations in developing brains, which leads to a higher risk of developing certain psychiatric disorders, including autism, ADHD, schizophrenia, bipolar disorder, major depressive disorder, Tourette syndrome, obsessive-compulsive disorder, and anorexia.
this post was submitted on 09 Feb 2025
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It doesn’t sound super surprising that different malformations in the brain even though caused by the same underlying condition can result in very varied effects on behavior.
Good stuff though. (The research)
I don’t know if a pleiotropic relationship between 109 different genes can be called “the same root cause”. Maybe “a large complex of interacting causes”?
Fair point!
Interesting article. Thanks for this post!