this post was submitted on 11 Sep 2023
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I do not recommend you to do this in your backyard. And if doing this, just as a curiosity, not as a reliable production method; this is NurdRage tier, not "make bleach at home and avoid Big Tech" tier. That said, on a theoretical level, the synthesis would be simply
You'll probably get a 10% of junk compounds where the methyl attaches itself to the wrong carbon of the indole. Those could be separated by careful crystallisation.
As long as you take the proper security procedures, this is fairly safe. One of my uncles work with car soldering, and he produces acetylene at home.
Kind of hypocrite of me to say that, given that I have a scar on one of my arms from one of those reactions, but to be fair most people aren't as stupid as a 14yo mixing calcium carbide and water inside a glass bottle, and closing it. (It was 20 years ago. My family still mentions this.)