this post was submitted on 28 Apr 2025
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Science Memes

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submitted 1 day ago by [email protected] to c/[email protected]
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[–] [email protected] 13 points 1 day ago (1 children)

Compliance wasn't an issue since we we ran the study in mice and they all liked the food. they're all basically clones so so it helps eliminate a LOT of variables. As expected we found the 60% diet induced a much more dramatic phenotype than the 40% but both induced obesity in general, but even ONLY having 60 vs 40% fat the differences were significant enough to make me reluctant to compare the two HFDs especially when you dive into microbiota stuff. I wouldn't say its apples and oranges, more like apples and crab apples... or something.

[–] [email protected] 8 points 1 day ago (1 children)

Oh, ok. I just assumed a human study, but mice makes more sense. It certainly sounds like an interesting study. I find nutrition to be an engaging topic, especially considering the availability of choices that many have now. Thank you for answering my questions!

[–] [email protected] 10 points 1 day ago

no worries, I love talking about work! Nutrition is especially interesting given how relevant it is in our day to day lives and how complicated everything is between food itself, genetics and our gut microbiome. I could read about it all day, and not because I had to for two years!