this post was submitted on 25 Mar 2025
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[–] [email protected] 8 points 1 week ago (3 children)

Finally, someone speaking actual biology instead of paranoid rants. Impressive grasp of glycosylation and conserved epitope exposure - you've clearly done your reading beyond headlines. The sugar-stripping approach is ingenious precisely because it targets what viruses try to hide. Current research trajectory looks promising but I'll wait for peer-reviewed publications after that ACS meeting before joining the hype train.

🐱🐱🐱🐱🐱

[–] [email protected] 1 points 1 week ago (1 children)

Does the sugar stripping affect any other bodily functions? Stripping is temporary but it still may have permanent effects for some existing conditions.

Does a coronavirus need to be introduced at the same time sugars are stripped or is it assumed that there are already many in the body?

[–] [email protected] 1 points 1 week ago (1 children)

Ok, you're missing a bit here. The "sugar stripping" happens in the lab, during the production of the immunogen, which would then later applied as a vaccine. From there the vaccine induces a response from the immune system, creating antibodies which are specific to the highly conserved part of the stalk structures on corona viruses. As a result one's immune system is prepared for when a corona virus shows up at some point after the vaccination.

[–] [email protected] 2 points 1 week ago

Ah. Yes. I was thinking the sugar stripping happened in the body. So this more a vaccine enhancement tool.

[–] [email protected] 1 points 1 week ago

I've learned a lot more about virology, vaccines, and immunology in the past 5 years than I ever thought I would need/ want to know, mostly from listening to the brilliant folks over at Microbe.TV (https://www.microbe.tv/), with This Week in Virology, and the other science based podcasts they produce.

[–] [email protected] 1 points 1 week ago* (last edited 1 week ago) (1 children)

i was thinking the same about the abstract, the glycans were shielding the conserved parts epitopes that arnt prone to mutations, as opposed to the exposed parts of the proteins which the virus mutates much more rapidly. you can say the conserved parts can mutate, but it might compromise the structure of the protein, making the virus defective(it probably does happen, but they dont survive)

[–] [email protected] 1 points 1 week ago

Mutations will always happen, it's what viruses do.