World News

32317 readers

793 users here now

News from around the world!

Rules:

Please only post links to actual news sources, no tabloid sites, etc
No NSFW content
No hate speech, bigotry, propaganda, etc

founded 5 years ago

MODERATORS

[email protected]

219

Why a highly mutated coronavirus variant has scientists on alert (www.nature.com)

submitted 1 year ago by [email protected] to c/[email protected]

12 comments fedilink hide all child comments

you are viewing a single comment's thread
view the rest of the comments

[–] [email protected] 11 points 1 year ago (2 children)

T cells.

“Most studies on COVID-19 vaccines have focused on neutralizing antibody (NAb) responses, with little emphasis on cellular immunity. However, accumulating data suggest that T cell responses play an important role in vaccine protection against severe COVID-19 disease, particularly against viral variants that partially escape from recognition by NAbs. These insights have implications for using current COVID-19 vaccines and for developing next-generation vaccines against COVID-19 and other infectious diseases”

science

[–] [email protected] 9 points 1 year ago* (last edited 1 year ago)

@notacat speaking of those -- there is evidence that SARS-CoV-2 sticks around and causes chronic T cell activation, and there are only so many naive T cells the thymus can supply before it shrinks (it normally shrinks with age)

This implies that all covid infections, even those that don't produce obvious long covid at first, may be prematurely aging the immune system

https://www.medrxiv.org/content/10.1101/2023.07.27.23293177v1.full