It seems like the benefits are having the device lock/wipe itself after a set amount of attempts in case of a brute force attack and not having to run software to decrypt the drive on the device you plug it into.
I included a picture of the IronKey Keypad 200 but that's just because it's the first result that came up when I was looking for an example. There seem to be a few other manufacturers and models out there and they probably have different features.
I am curious what do you think of them? Do you think they are useful? Do you find it more a novelty?
It was an ExplainingComputers video titled Very Useful Small Computing Things that made me think of them.
Ah it was easy enough to get the iron key unlocked during post, as those HP servers take forever to boot, problem was the bios couldn't recognize the USB. Whatever firmware is on it that does the security confused the system, and while it saw the drive, it didn't know what it was and wouldn't boot from it. In both uefi mode, and in legacy bios mode