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Study reveals why women are at greater risk of autoimmune disease (med.stanford.edu)

submitted 9 months ago by [email protected] to c/[email protected]

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[–] [email protected] 4 points 9 months ago (1 children)

@Gaywallet This particular link wasn't opening for me. But what I have heard elsewhere is that there are indeed known to be a number of parts of the X chromosome which affect the immune system, in ways we are still in the process of figuring out.

[–] [email protected] 2 points 9 months ago

It's an interesting article, and well exposed.

It basically goes to say that the inactivation mechanism (Xist noncoding RNA strand) which gets triggered when there are two X chromosomes present in a cell, almost completely coats one of the X chromosomes, disabling it... but the result is not completely inert, still allowing the attachment of other partial strands, in weird combinations that can lead to an (auto)immune response.