this post was submitted on 25 Feb 2024
507 points (90.6% liked)

Cool Guides

4650 readers
2 users here now

Rules for Posting Guides on Our Community

1. Defining a Guide Guides are comprehensive reference materials, how-tos, or comparison tables. A guide must be well-organized both in content and layout. Information should be easily accessible without unnecessary navigation. Guides can include flowcharts, step-by-step instructions, or visual references that compare different elements side by side.

2. Infographic Guidelines Infographics are permitted if they are educational and informative. They should aim to convey complex information visually and clearly. However, infographics that primarily serve as visual essays without structured guidance will be subject to removal.

3. Grey Area Moderators may use discretion when deciding to remove posts. If in doubt, message us or use downvotes for content you find inappropriate.

4. Source Attribution If you know the original source of a guide, share it in the comments to credit the creators.

5. Diverse Content To keep our community engaging, avoid saturating the feed with similar topics. Excessive posts on a single topic may be moderated to maintain diversity.

6. Verify in Comments Always check the comments for additional insights or corrections. Moderators rely on community expertise for accuracy.

Community Guidelines

By following these rules, we can maintain a diverse and informative community. If you have any questions or concerns, feel free to reach out to the moderators. Thank you for contributing responsibly!

founded 1 year ago
MODERATORS
 
you are viewing a single comment's thread
view the rest of the comments
[–] [email protected] 19 points 8 months ago (4 children)

Keep in mind: a single extra strength Tylenol is 500mg. A standard dose for a headache is 2 pills, or 1000mg.

Weed gummies come in doses of 1mg to 100mg. 1mg is a microdose people might take for mild pain or stress, while 50+mg is a dose for cancer patients often take. A standard dose for occasional recreational highs is 5mg; they recommend first timers start at 2.5mg.

LD50 compares things by weight, rather than dose. By weight, THC is slightly more toxic than acetaminophen. But in terms of the number of therapeutic doses it takes to kill you, it's way, way safer.

[–] [email protected] 6 points 8 months ago (3 children)

Yes, I came here for this conversation. What's the ratio of effective dose to LD50 again, because that's typically what matters. That's where cannabis and ethanol are in totally different categories. And how high do you need to get before dying from LSD?

[–] [email protected] 4 points 8 months ago (1 children)

16.5 mg is 16500 μg. So a 70kg person would need over 1 million μg.

According to https://www.trippingly.net/lsd/the-lsd-dosage-guide, 25 μg is where visual effects start.

700 to 1000 μg. Full out-of-body experiences. Synesthesia more likely. Religious imagery often strong. Entire loss of rationality, lack of ability to walk or interact in any meaningful way.

1500 μgs+ Experiences may be similar to DMT but extended. Basic body functions are challenging. Vision is consumed by hallucinations. No sense of self remains. Audio hallucinations may be strong. Standard reality no longer applies. Merging with objects likely. No type of rational thought left.

A deadly dose is around 800x higher than that. You wouldn't be as high as a kite. You'd be as high as Voyager one.

[–] [email protected] 3 points 8 months ago
load more comments (1 replies)
load more comments (1 replies)